KMID : 1094020060230020194
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Journal of Veterinary Clinics 2006 Volume.23 No. 2 p.194 ~ p.196
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Renal Leiomyosarcoma with Hepatic Metastasis in an Asian Water Buffalo (Bubalus arnee)
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Cho Ho-Sung
Kim Yeong-Seob Park Nam-Yong
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Abstract
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A leiomyosarcoma that occurred in the right kidney with hepatic metastasis of a 15-year-old intact female Asian water buffalo (Bubalus arnee) in a zoo, Republic of Korea. The animal showed no clinical signs. Grossly, a firm and white mass (6.0 x- 5.0- x 4.0 cm) was observed in the renal capsule and multiple firm white nodules, measuring 1.0-2.5 cm, were present on the surface of the liver. Microscopically, tumor cells were spindle-shaped, the cell density was high, and complex fasciculated tumor cells showing longitudinal and transverse cross-sections were observed. Tumor cell nuclei was ordinarily cigar shaped and had rounded blunt ends. Immunohistochemically, tumor cells reacted intensely with anti-smooth muscle actin antibody. This is the first case report of a renal leiomyosarcoma with hepatic metastasis in a Asian water buffalo.
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KEYWORD
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leiomyosarcoma, kidney, hepatic metastasis, Asian water buffalo
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